Medicinal Chemistry

The information gathered can help confirm the cause of health concerns or rule out any potential concerns which are a critical tools in helping healthcare providers understand.
Overview
Medicinal chemistry contract research services at SynSmart involve a specialized team of scientists working in close collaboration with industry leader scientists and computational chemistry experts for mg to kg scale chemistry requirements.

SynSmart is proficient in developing methodologies, including the synthesis of single, multi-step, and small arrays as well as designing the focused libraries for use in hit-to-lead and lead optimization projects.

A medicinal chemistry project involves the SynSmart team suggesting Structure Activity Relationship (SAR) ideas for consideration based on information regarding target of interest and earlier iterations to scaffolds of interest. Once the scientific approach is agreed with our partners, SynSmart takes the lead in synthesizing compounds for optimization, leading to candidate selection.

The compound delivery is accompanied with characterization data including high-field NMR, and mass and purity by LC-MS/HPLC/GC. Also, the Supercritical Fluid Chromatography aids chiral separation and generates a higher throughput.
Column chromatography chemistry in the lab.

What We Do?

An expanded panel of essential, conditionally essential amino acids, and non-essential amino acids provides clinical utility and supports the development of personalized treatments. A formula for a customized amino-acid blend is provided with each report, offering suggested replacement amounts based on test results.

Investigations Price List

Umbilical Cord Appearance
$50
Cardiac Electrophysiology
$80
Repositioning Techniques
$60
Geriatric Neurology
$75
Nuclear Cardiology
$45
Neurocritical Care
$55

Treatments Price List

Colonoscopy
$50
Allergy testing
$80
Gastroscopy
$60
Bronchoscopy
$75
Cardiac Ablation
$45
Holter monitoring
$55

Health Tips & Info

Additionally, children’s reference ranges are designed to provide more accurate pediatric nutritional evaluations. Identifying metabolic blocks that can be treated nutritionally allows individual tailoring of interventions that maximize patient responses and lead to improved patient outcomes.
Organic acids are metabolic intermediates produced in pathways of central energy production, detoxification, neurotransmitter breakdown, and intestinal microbial activity. Accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This abnormality may be due to a nutrient deficiency.
Organic acids are metabolic intermediates produced in pathways of central energy production, detoxification, neurotransmitter breakdown, and intestinal microbial activity. Accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This abnormality may be due to a nutrient deficiency.
Organic acids are metabolic intermediates produced in pathways of central energy production, detoxification, neurotransmitter breakdown, and intestinal microbial activity. Accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This abnormality may be due to a nutrient deficiency.
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