New Advanced Instruments
About the service
SynSmart provides comprehensive ADME-PK support to generate critical insights into the absorption, distribution, metabolism, and pharmacokinetic properties of drug candidates. Our capabilities span in vitro and in vivo studies, enabling the assessment of solubility, stability, metabolic behavior, protein binding, CYP interactions, permeability, and pharmacokinetic profiles. These studies help identify potential liabilities early, guide compound optimization, and support informed decision-making as programs progress from discovery toward development.
DMPK - In vivo
Single Dose PK Studies
Cross Over Studies
Multiple Dose PK Studies
Toxicokinetic Studies
Dose Range Finding Studies
Dose Escalation Studies
Maximum Tolerable Dose Studies
DMPK - In vitro
Kinetic Solubility
Thermo-dynamic Solubility
LogD
Plasma Stability Study
Protein Binding Study
Microsomal Metabolic Stability
Microsomal Metabolic Stability
Blood to Plasma Ratio Determination
Chemical Stability Study
Direct CYP Inhibition Studies
CYP Time Dependent Inhibition Studies
PAMPA
Hepatocyte Metabolic Stability
CYP Induction
Caco-2
MDCK
Accelerate your design-make-test
Cycle with SynSmart
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Share your requirements, project goals, or specific chemistry challenges .
SynSmart Rasayan Research , Navi Mumbai, Maharashtra 400701, India
bd@synsmart.in
+91 84540 99758
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