ThinkMolecular’s Offerings:
Structure Mining Leveregaed Drug Design (SmiLeDD) is a computational drug design platform developed at thinkMolecular. The platform is a collection of a variety of proprietary, open-source and in-house tools that leverages the structural information of the target, biological data of known binders and associates the compounds with their plausible bioactive conformations in the targets. Thus, with the knowledge of the interaction hotspots and bioactive conformations, we design new compounds using denovo, fast follow-ons, fragment linking or any other suitable approach.
Working alongside the medicinal chemistry teams and with laser sharp focus on the target product profile, we refine our predictive models with program specific data and enhance the possibilities of success. Along with the structure-based models for target specific designs, we predict ~50 DMPK properties and prioritize compounds for synthesis based on multi parameter optimization.
is both a blood and urine test that evaluates over 125 biomarkers and assesses the body’s functional need for 40 antioxidants, vitamins, minerals, essential fatty acids, amino acids, digestive support, and other select nutrients. Personalized recommendations for nutrients are determined by using an algorithm based on the patient’s test findings.
The Bloodspot Amino Acids 20 Profile is a finger-stick amino acid test that can uncover problems in amino acid absorption and metabolism by determining amino acid imbalances in the nine essential amino acids, four conditionally essential amino acids, and seven additional amino acids.
An expanded panel of essential, conditionally essential amino acids, and non-essential amino acids provides clinical utility and supports the development of personalized treatments. A formula for a customized amino-acid blend is provided with each report, offering suggested replacement amounts based on test results.