Library and Analogs
Variety of libraries ranging between focused libraries 10-100 members. Our capabilities include synthesizing libraries, synthesis of scaffolds/building blocks including complex structure involving multi-step synthesis.
Synthesis of O, N, S and P heterocyclic and fused-ring analogues, Benzofuran formation, Azaindole Chemistry, Thiophene ring formation, Thiazole formation etc.
Suzuki coupling, Negishi & Heck Coupling, Buchwald-Hartwig Coupling, Phosphonate Chemistry, C-P, C-S, C-B, C-Sn and C-Si bond forming reactions, C-H activations etc.
Including all kinds of metal-based pyrophoric reagents like lithium, magnesium and zincs, toxic reagents like metallic cyanides and metal carbonyls e.g., Reduction, Catalytic hydrogenation, Grignard, Hydroxymethylation etc.
Experienced in reactions involving gases like H2, Cl2 , O2 , CO, CO2, SO3 etc. – in addition to rarer reactions like ozonolysis – even at larger scales. e.g. Chloromethylation, Bromination & Selective Reduction, all types of Halogenation
Cryogenic Reactions, Use of pyrophoric reagents, fluorinations, synthesis of fluoroalkyl and fluoro alkoxy targets, cyclopropanations, deuterations, labeling and isotope synthesis and much more.
From building blocks to complex molecules, we deliver high-quality synthetic chemistry to accelerate your discovery and development programs.
Variety of libraries ranging between focused libraries 10-100 members. Our capabilities include synthesizing libraries, synthesis of scaffolds/building blocks including complex structure involving multi-step synthesis.
We have capabilities of synthesis and screening of different catalysts, e.g. Iridium complexes, Vanadium complexes etc.
SynSmart team has the ability to synthesize a wide variety of molecules, including nucleotides and nucleosides.
Chemistry of PROTACs and partial PROTACs. Our team of experienced organic chemists can tackle the synthesis of heterobifunctional target molecules used for Protein Degradation.
Asymmetric aldol and related reactions, asymmetric Diels-Alder reaction, asymmetric transfer hydrogenation, asymmetric reductions, asymmetric dihydroxylation, amino hydroxylation, symmetric hydrosilylation, resolution of racemic mixture.
Our team has experience of synthesis of a wide range of carbohydrate-based compounds.
We have capability to separate chirally pure compounds via crystallization, resolution, prep HPLC purification.
We are experts in metabolite synthesis.
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CEO’S MESSAGE • SEPTEMBER 2026
As SynSmart completes its expansion to add a brand new site under its fold, we are looking to make rapid progress in multiple geographies. Our total site footprint now stands at 25,000 sft and with 70 fume-hoods of installed capacity, we are ready to take on opportunities at scale.
The key elements of our ability to deliver can be best summarized in what we bring together in terms of People, Processes and Technological Advantage.
Our People are central to everything we do and have consistently gone above and beyond in delivering customer projects against all odds. We are continuing to bring in people to expand our talent pool and in doing so, we seek people who resonate with SynSmart’s values of Passion, Learning, Team-work and Customer Centricity.
On Processes, we are continuing our journey to stay ahead in the technology game. With tools like SciFinder and ChemDraw we are also adding AI-enabled solutions to further help our teams.
SynSmart has a bold capital deployment plan with investments exceeding $1M lined up to both augment capacity and strengthen the service offerings.
In terms of capability strengthening, addition of flow chemistry capability with a daily through-put of over 5L is one of our key highlights for the year and we are on-track to deliver multi-Kg through-put with this set-up.
Similarly, we have now brought onboard a Bruker Avance III 400MHz NMR to help rapid data generation for compound delivery. Further investments in analytical infrastructure include onboarding multiple UPLC-MS machines.
Overall, SynSmart in 2026 is raring to go and ready for taking on any chemistry challenge presented to us.
Saurabh Kapure
CEO, SynSmart
